CV of / Manager in production or development department , looking for a job of Chemical industry, Pharma, medical /

Cv de manager in production or development department

open ended/ chemistry/pharma/Switzerland / [Chimie / Pharmaceutique / Suisse]

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CV Code: 9a946c42fa96d384
Date of last connection: 2014-04-01

Mr. Ju... G...


2000 Neuchatel

Current situation:

Total working experience: None

Job sought:

Positions: manager in production or development department, ,

Industry: , ,

Desired type of contract: open-ended contract

Desired working time:

Minimum annual salary desired: 0.00 / 0.00 EUR


Highest educational level completed: number of years studied and completed with a diploma after highschool :

Last diploma :

Current educational level :

Other training courses : Sciences, Chisinau, MD).
Title: Complexes of Iron, Cobalt, Nickel and Copper with Quadridentate Ligands Based on S-substituted Thiosemicarbazide and β-dicarbonyl Compounds.
Main achievements
- Synthesis and characterization of 35 new coordination compounds.
Specific skills
Template synthesis - Crystallization for X-ray studies.

1981 – 1986 MS Inorganic Chemistry (Prof. A. Gulea, Dept. of Chemistry, Moldova State University, Chisinau, MD)
Title: Synthesis and NMR study of the cobalt(III) dioximate with tin halogenates.

Divers :

Geographical mobility: unreported

Known Tools / Software/ Methods

HGV, LGV, special vehicles licences



Mr. Ju... G...


2000 Neuchatel

01.10.2008 - till now. Scientist, responsible of pilot study, PDVR (Development Department), Medical SA, Crissier (Department manager: Dr. Vincent Adamo)
- Responsible of hydroxyethylstarch project development study and up-scaling process. Preparation of study protocols, MBR, analysis of obtained results, review of critical parameters, recommendations and advice on follow up, contribution to study meetings providing relevant study information, preparation of development protocols and reports, as well as review of literature in the starch field.
- Support the Production activities by the improvement of MBR and desired API characteristics in order to better matching to the middle of specifications, study of waste water problems and toxic impurities elimination etc.
- To manage other development spin projects as carboxymethylated starch synthesis and drug delivery starch derivatives.
- Participation in on-going waste water treatment project as expert-chemist, presentation of concept of chemical treatment to the local authority SESA VD, participation on analysis risk elaboration with environmental safety department.
06.2008-08.2008 Postdoc ( Inst. of Chemistry, University of Neuchâtel, CH).
Research topics: : Synthesis of new arene-ruthenium antitumoral complexes.
10.2007-02.2008 Postdoc (Prof. Th. R. Ward, Inst. of Chemistry, University of Neuchâtel, CH).
Research topics: nano-thechnology assembling of one-dimensional metal-org. protein framework (MOPF) introducing the streptavidin (as a linker) between two FeII (terpyridine-bis-biotin) connectors.
09.2006- 09.2007 Scientific collaborator Unine (Development) (Joint project Debiopharm S.A. Lausanne & UNI Neuchâtel, CH).
Position topics: Synthesis of new antitumoral oxaliplatin derivatives (for preclinical & clinical studies). - Fully characterization with physico-chemical methods (MS, 1H, 13C,195Pt, UV-vis) in order to establish their properties and structures.
- Collaboration with Synthetic API Development Manager Ph.D Judith MARFURT.
Main achievements
- Successful achievement of the project. - 195Pt RMN. - GLP working & documentation preparation. - Customer-oriented scientific communication.
09.2005 – 09.2006 Project Leader Unine (Development) (Joint project Metalor S.A. Neuchâtel & UNI Neuchâtel, CH).
Research topics: Optimization and shortening of cisplatin and carboplatin synthesis in order to start the industrial production.
Main achievements
- Development of a new one-step cisplatin synthesis from tetrachloroplatinate and pharmacopea-grade purification.
- Development of a new one-pot synthesis of carboplatin from cisplatin with direct isolation of final product and pharmacopea-grade purification. Upscale to mini-pilot.
- Collaboration with Nsenda, Technical Manager Pharma.
2001 - 2006 Postdoc (maitre assistant) (Prof. Th. R. Ward, Inst. of Chemistry, University of Neuchâtel, CH).
Research topics: Production of artificial metalloenzymes for enantioselective catalysis (biomimetic spirit). Application of biotin-avidin technology.
Main achievements
- Synthesis of biotinilated derivatives of amidodiphosphine, porphyrine, bipiridine, Schiff bases, polycompartmental ligands. - Catalytic hydrogenations. - Manipulation and purification of air-sensitive molecules (Schlenk technique) - Publication of results as author in 7 scientific papers (abstracts available upon request). - Improved analytical approach to solving technical problems occurring in chemistry. - Multidisciplinary scientific communication.
- Synthesis of new molecules - Purification and analytical studies. - Training and supervision of PhD students, MS students and technical staff. - Teaching assistant in regular and practical courses of analytical chemistry for biology and chemistry students.
1993 - 2001 Senior Scientist (Prof. Inst. of Chem., Moldova Academy of Sciences) .
Research topics: Template synthesis of new metal complexes with macrocyclic and non cyclic ligands with antibacterial, pigment, non linear optic properties.
Main achievements
- Single-step assembly of macrocyclic and chelate 3d complexes. – Physico-chemical studies - Publication of results as author in 35 scientific papers and 4 patents.
- Synthesis of new molecules - Purification and analytical studies. - Membership in the Organizing Committee of the XIV-th conference “Physical methods in Coordination and Supramolecular Chemistry” (Chisinau, Moldova). Supervision of PhD students, MS students. - Teaching assistant in regular and practical courses of inorganic chemistry.
1986 - 1989 Laboratory Assistant (Prof. M. Revenco, Dept. of Chem., Moldova State University, Chisinau, MD).
- Preparation of reaction solution for the teaching purposes – Preparation of the laboratories. - Teaching assistant in regular and practical courses of analytical chemistry.

Cover letter

Mr. Ju... G...


2000 Neuchatel

Open ended/ chemistry/pharma/Switzerland / [Chimie / Pharmaceutique / Suisse]

Dear Sir,
Following your on-line advertisement I apply for the position of Production Chemist. This position matches with my aspiration of working for an innovative chemical company. I’m looking for new exciting professional challenges, and the possibilities for professional and personal development offered by this fulfil entirely my short and long term objectives.

I am currently working in Development department Medical SA (Crissier). I am in charge of pilot synthesis and study of new plasma volume replacement solutions. I am directly involved in up-scaling process and in validation and audit preparation. My main responsibilities are the preparation of manufacturing batch records (MBR), critical analysis of obtained results, recommendations and reports preparation. I take part also in the solving of current productions problems: improvement of API parameters, waste treatment etc, as well as in the development of the new research subjects, such as drug delivery systems based on starch derivatives via hesylation reaction or starch amino- functionalization etc.

As, I took part in the anticancer research projects the position of chemist in your company which is equal to a creative job is especially interesting for me. Your advertisement looks very promising for me, giving a new opportunity to diversify my professional area of activity.

I am dynamic person which done the main part of professional carrier in academic system. From 1993 till 2001 I worked at the Institute of Chemistry Moldavian Academy of Sciences and from 2001 till September 2008 at the Institute of Chemistry, University of Neuchâtel in the field of anti-tumour compound syntheses, and creation of artificial metalloenzymes for enantioselective catalyses. During my work at Neuchâtel University I leaded two joint projects with well-known Swiss industries (Metalor, Neuchâtel, and Debiopharm, Lausanne).
My responsibilities as supervisor of PhD, diploma students and lab-technicians, and the fact that, in addition to my principal activity, I was in charge of practical courses of analytical chemistry have permitted me to further develop my communication and team-management skills.
I am equally comfortable working independently or as part of a team. Thanks to my international work experiences (UK, Germany, Italy), innovative aptitudes, as well as the ability to speak several languages (English, French, Russian, and Romanian), I easily adapt to multicultural environments.
I am a co-author of 35 articles and 4 patents and I have experience in literature and patent search, as well as their critical analysis and easy handling. The experience I have acquired in both organic and inorganic synthesis in industrial and academic area multiplied by my innovation, positive attitude and persistence would be a valuable contribution to the potential of your company. I would be glad to further discuss more aspects regarding my qualifications as well as the details of the position available. I look forward to hearing from you soon.

Mr. Ju... G

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